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Cold-Chain Bioprocessing Applications
Aramus™ single-use bag assemblies are ideal for cold chain collection and storage. Our single-layer fluoropolymer provides gamma stability with low extactables and leachables (E&L) and has a wide operating temperature range.
Our bag assemblies, tubing, and connectors can be adapted to a number of SUS configurations, making Aramus single-use bag assemblies a flexible and dependable choice for cold bioprocessing applications.
Featured Content
Featured Content
Featured Content
Advantages of Single-layer vs. Multilayer Film for use in Cold-Chain Bioprocessing Applications
Our video highlights one of the most common single-use bag failures and how that can affect valuable bioproducts. Aramus™ bag assemblies overcome these failures at cold temperatures using a new single-layer fluoropolymer material that protects product by its durability at a wider range of temperatures than in other single-use-systems (SUS).
RECENT WEBINARS
Risk Mitigation for Single-use Cold Chain Distribution
In this webinar, we will share risk mitigation study data showing the utility of low temperature suitable materials and packaging, employment of sensors for monitoring shipments, and better qualification and evaluation through simulated standards and real-world transit.
Bulk Drug Substance: Freeze/Ship/Thaw Systems
In this previously recorded webinar, Mike Johnson, director R&D engineering of Entegris and Johannes Kirchmair, CEO/founder of Single Use Support (SUS), present single-use bag system technologies for freeze/thaw applications in bulk drug substance (BDS) manufacturing.
Featured Technical Paper
Rapid Scale-Up of Cold-Chain Operations in Drug Development and Manufacturing
This paper discusses the cold-chain supply scale-up challenges that can threaten product integrity during freeze/thaw, storage, and shipping, and the importance of empowering manufacturers to implement efficient, cost-effective solutions.
Featured Technical Paper
Low Risk Frozen Distribution of Single-Use Bags for Bioprocessing
This paper discusses the results of a frozen shipping study of single-use fluoropolymer bags conducted following new guidelines that help to mitigate the risks during frozen shipping and ensure consistent product quality in cold chain.
Featured White Paper
Advantages of Single-layer Film vs. Multilayer Film for use in Bioprocessing Bags
This paper takes a closer look at various storage bag materials used in bioprocessing applications, the challenges associated with them, including gamma stability, E&L, and low temperature usage, and the technological developments addressing these challenges. Specifically, it focuses on materials that enable an evolution (or a transition) from multilayer to single-layer storage solutions.
Featured White Paper
Employing Single-use Technology to Control Frozen Bulk Drug Storage
This paper addresses the challenges of bulk drug substance (BDS) storage, shipping, and other critical factors users must consider in deciding whether and how they will adopt single-use technology.
Featured Pictogram
Resilient Plastics in the Cold Chain
Pictorial that explains the advantages of single-layer fluoropolymer bags in the cold chain vs. multilayer bags, and how Aramus™ single-use bag assemblies can withstand gamma irradiation and cold-chain temperatures down to -196°C.
Featured Article
This article illustrates why the Aramus™ single-use bag assembly is the kind of material innovation the industry agrees it would like to see (according to a BioPlan report survey). Constructed from gamma-stable fluoropolymer, our Aramus single-layer bag assembly is put through a cold crack test at temperature intervals down to -188°C.
Avoid stability and quality concerns with Aramus™ assemblies that protect your bioproduct.
Avoid stability and quality concerns with Aramus™ assemblies that protect your bioproduct.
Recorded Webinar
Advanced Materials for Single-Use Biomanufacturing Systems
Learn how utilizing advanced fluoropolymer materials in single-use systems offers distinct advantages in regards to extractables, chemical compatibility, and cold temperature performance.
Striking Results!
See a cold temperature performance test of the Aramus™ film and two other materials, multilayer polyethylene and single-layer polyolefin, used in making single-use bags. Each material is placed in liquid nitrogen at -196°C for 30 seconds. The difference in this video is striking.
Featured Presentation
Single-Use Bag Permeability Testing in Cryopreservation Conditions
The stability of frozen solutions stored in single-use bags is a primary concern in bioprocessing. This presentation shares pH stability data from a frozen solution stored in single-use bags with different gas permeation rates that are subjected to CO2 gas from sublimating dry ice.
Featured Product
Protect your high-value fluids with reduced risk of product loss, contamination or compromised quality
- High-grade, gamma-stable fluoropolymer
- New single-layer technology, and no binders, agents or adhesives
- Durable in frozen applications (to -85°C [-121°F] or lower)
- Universal material compatibility
Learn more about the Aramus™ 2D Single-Use Bag Assembly.