Subvisible particles detection in parenteral drugs

Parenteral drugs are delivered into the body by directly injecting into the intravenous, subcutaneous, or intramuscular routes. Subvisible particle counting in parenteral drugs is described in USP <788>, a common application for the AccuSizer® SIS system. The same system can also be used for USP <789> test for ophthalmic solutions and the new USP <787> test for therapeutic protein injections.

The USP <729> test for globule size distribution in lipid injectable emulsions calls for systems like the AccuSizer APS for Method II and the Nicomp DLS system for Method I.

Featured Application Note

Effect of Silicone Oil Droplets in Pre-Filled Syringes