Particle Characterization

High Resolution Particle Size Analyzers and Particle Counters

What is a particle? The simplest definition is a minute portion of matter. Particle characterization is the process of identifying the particle size, particle shape, and surface properties. Analyzing particle behavior is a critical factor for quality control and product performance in many different industries. As product requirements continue to become more stringent, it is essential to understand particle behavior and reduce particle contamination sources. Particles measured by the techniques described here include solids (powders), solids in liquids (suspensions), and liquid/liquid emulsions.

There are many analytical techniques available for particle size measurements. Various techniques have different capabilities and dynamic range as well as assorted strengths and weaknesses. Before choosing an analytical technique, the user should first define what is required by the instrument and how the data will be used.

AccuSizer® systems are based on our unique single particle optical sizing (SPOS) technology. The AccuSizer SPOS system is both a liquid particle counter and a sophisticated particle size analyzer. Particles are sized and counted one at a time as they flow through a sensor inspection zone. This creates high accuracy, high resolution particle size distributions as well as concentration data in particles/mL. 

The AccuSizer SPOS system is the industry standard in detecting tails of distribution in CMP slurries with the highest sensitivity technology available. Beyond semiconductor, the pharmaceutical industry uses the AccuSizer system to detect large particles in lipid emulsions, for USP <788> testing, and for protein aggregation studies.  

Each system includes an SPOS sensor, a pulse height analyzer (or counter), and fluidics to transport the sample through the sensor. Many systems include automatic dilution to adjust the concentration to the optimal range for measurement. A range of both laboratory and online systems are configured to specific application requirements.

Our Nicomp® Nano dynamic light scattering (DLS) systems measure size and zeta potential of submicron particles. Using dynamic light scattering technology, the Nicomp DLS system can size proteins, colloids, emulsions, nanoparticles, CMPs, inkjet inks, and a variety of other dispersions used in nanotechnology and medicine. Designed for sensitivity, the Nicomp system algorithm is uniquely capable of determining when multiple peaks are present and can resolve peaks closer than any other DLS system. 

Major benefits of owning a Nicomp DLS system include high-resolution particle size analysis, high-accuracy zeta potential results, and a system custom-tailored to your needs, providing optimal results. Advanced options including multi-angle goniometer, autodilution, auto-sampling, and online systems make the Nicomp system the best choice for many samples.