Particle Characterization
Particle size is a critical physical parameter that affects function and performance in the chemical, semiconductor, and pharmaceutical industries. Whether you're dealing with powders, suspensions, or emulsions, uncontrolled particle size and contamination can lead to product failure, regulatory issues, or costly recalls. The Entegris AccuSizer® and Nicomp® particle size analyzers are designed to identify, control, and optimize particle characteristics with unmatched accuracy and resolution.
Your Challenge: Detecting and Controlling Problematic Particles and Process Deviations
Our Solution: High-Resolution, Application-Specific Particle Analyzers
Featured Product Solutions
Problem Solved: The optimal solution to detect oversized particles that compromise product quality
How We Help: Our Single Particle Optical Sizing (SPOS) technology counts and sizes each particle individually, delivering high-resolution size distributions and accurate concentration data (particles/mL).
Industries Served:
- Semiconductors: Detect tails in CMP slurry distributions
- Pharmaceuticals: Comply with USP <788>, <787>, <789>, <730> and monitor protein aggregation
- Chemicals: Suspensions, inks, emulsions, and coatings
Key Features: Automatic dilution, real-time analysis, lab and online configurations
Problem Solved: Struggling to analyze submicron particles or resolve overlapping size populations?
How We Help: Our Dynamic Light Scattering (DLS) systems offer high-resolution sizing and accurate zeta potential measurements, even in complex samples.
Industries Served:
- Nanotechnology & Biotech: Analyze proteins, nanoparticles, emulsions, and colloidss
Key Features: Multi-angle goniometer, auto-sampling, autodilution, and online options
Why Choose Us?
- Tailored Solutions: Systems configured to your specific application needs
- Regulatory Confidence: Meet stringent industry standards with ease
- Operational Efficiency: Reduce downtime and improve product consistency
- Expert Support: Backed by decades of particle analysis expertise
Featured White Paper
Tails of Distributions White Paper
Learn about the potential hazards to fluid performance found in the fine and coarse tails of distributions. Different methods to measure the effects of tails using techniques such as single particle optical sizing, dynamic light scattering, and zeta potential will also be explored.
Featured White Paper
Particle Size Analysis Overview
New to particle size analysis? This paper reviews different analytical techniques for particle size analysis, including types of distributions, laboratory versus online systems, and sample result comparisons. It is intended to help scientists new to particle size analysis understand each technique’s various strengths and weaknesses in order to select the proper technique for their samples.
Featured Webinars
Addressing the Options and Challenges in Subvisible Particulate Contamination Monitoring in Single Use Systems
Key learning objectives:
- Contamination measurement for visible and subvisible ranges, evaluated using different techniques.
- Equipment and methods for testing for submicron particulates with sizes below the USP <788> limits of 10 and 25 µm.
- How ASTM E3230 provides a helpful framework for testing particulates below USP <788>
- Extraction method development and effects onresults
Accurately Quantifying Tails of Particle Size Distributions AZO webinar
Learn how to use techniques such as single particle optical sizing to accurately characterize particles in the tails of distributions, which can help optimize fluid performance.
Particle Sizing in Additive Manufacturing Powders: SPOS vs. Laser Diffraction Comparison
During this AZO Materials webinar, sponsored by Entegris, with Mark Bumiller, technology manager, we’ll cover:
- The importance of particle sizing
- Different particle sizing techniques
- Interpreting data from SPOS & laser diffraction
- The importance of fines and tails
Particulate Contamination in Medical Devices and Single-Use Systems
Subvisible particulate testing is critical to assess the safety of medical devices, & particulate contamination should be minimized to avoid possible negative health consequences to the patient. A wide range of standards, USP tests, & FDA guidance documents provide test methods & acceptance criteria for particulate contamination in medical devices.
Particle Characterization of Specialty Chemicals
Topics include:
- Why particle characterization is critical to achieving the highest-value product formulations & performance
- Approaches to particle size analysis & the instrumentation used in the process
- How zeta potential predicts dispersion stability
- Industrial examples from: Inks, Emulsions, & Pigments
Featured Videos
Shining Light on Particles: Innovations in Online DLS Technology
Amanda Olson, technical writer for AMH instrumentation at Entegris, talks about our Mini DLS online particle sizing system. Watch the video to learn what makes the Mini DLS a vital and interesting technology both for its designers and our valued customers. Runtime:03:14
View the Accusizer SPOS System
Video introduction of our AccuSizer® SPOS systems comprising high resolution and high concentration particle counters that accurately determine particle size and counts at the tail end of your distributions.
View the Nicomp DLS system
Video introduction of our Nicomp® DLS systems that use dynamic light scattering (DLS) technology to provide high sensitivity, high resolution size, and zeta potential of sub-micron particles.
Featured Documentation
We have a comprehensive library of reference materials detailing how to apply our advanced particle count and size analyzers to solve a range of laboratory and process applications in semiconductor, life sciences, and other industries. Here is a sampling of our high-performance solutions.